ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Salivary plasminogen activator alpha 1

Intramolecular
Cysteine 257 and cysteine 273
A redox-regulated disulphide may form within Salivary plasminogen activator alpha 1 between cysteines 257 and 273 (42 and 58 respectively in this structure).

Details

Redox score ?
80
PDB code
1a5i
Structure name
catalytic domain of vampire bat (desmodus rotundus) saliva plasminogen activator in complex with egr-cmk (glu-gly-arg chloromethyl ketone)
Structure deposition date
1998-02-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
P98119
Residue number A
257
Residue number B
273
Peptide name
Salivary plasminogen activator alpha 1

Ligandability

Cysteine 257 of Salivary plasminogen activator alpha 1

Cysteine 273 of Salivary plasminogen activator alpha 1

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